Using the label-free optical technique of Bio-Layer Interferometry (BLI), the Octet® platform provides real time analysis of biomolecular interactions. It relies on the robust and easy to use Dip and Read™ format, which provides faster time to results relative to technologies like ELISA and SPR. It also operates in a fluidics-free format thereby minimizing the complexity in analyte detection by fluidics-based technologies like SPR. It provides high throughput analysis, with the option of analyzing up to 96 samples simultaneously, thereby increasing analytical productivity. It has high tolerance to a diverse array of sample types, lending itself compatible with in-process testing during drug substance manufacturing. In addition, the samples analyzed on an Octet system can be reused for other analysis, minimizing depletion of precious samples and maximizing process economy. In this poster, we will describe multiple ways in which the Octet platform is well suited for GxP and QC applications.