[eBook] Advances in Phenotypic Screening

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Phenotypic screening was the only strategy for drug discovery for many years until target-based approaches and genomics began to take center stage. Currently many pharmaceutical companies are implementing a more balanced strategy that utilizes both phenotypic and target-based approaches. This eBook will review the benefits of phenotypic screening, as well as some of the most burdensome challenges and the novel solutions that are emerging to address them. Topics covered in this ebook include:
  • Why phenotypic screening is experiencing a renaissance
  • The benefits of using flow-based methods as part of the phenotypic screening process
  • New methods to address target deconvolution
  • A comparison of flow-based and high content image based screening
  • Seven key attributes to better compound profiling