Adaptable, Reliable Solutions for Disconnection
As biomanufacturing increasingly adopts single-use solutions, reliable disconnections are critical for maintaining closed systems. Process integrity and operator safety depends on the technology. Plans to aseptically disconnect these systems must be part of the overall process plan to ensure proper containment.
User-friendly design based on years of customer feedback and experience.
Varied disconnection options to meet customers’ containment, cost and critical process needs.
Scalable thermal and mechanical disconnection technologies ease adoption of single-use technologies from R&D to commercial processes.
Sartorius offers a complete portfolio of disconnection technologies for single-use systems and unit operations. By matching process needs with disconnection technology capabilities, biomanufacturers can streamline and protect valuable process fluids. Review the solutions below to understand the range of options available.
Biosealer® TC
Clipster®
Quickseal®
Triclamp
Quick Couplers
Type of connection
Sterile
Non-sterile
Maintains Sterility in Non-classified Environments
Yes
No
Time
1-4 mins
45 secs
5-10 secs
1 min
< 30 sec
Cost per Connection
$ *
$$ **
$$$$
$
Fluid contact materials (aside from tubing)
None
Polyethylene, gasket & cap
Polycarbonate/ Polysulfone
Typical tubing material
TPE Only
TPE / Silicone
TPE / SIL / EVA
Size range
1/4" – 1" OD
1/4" – 3/4" OD
1/8" — 1.125" OD
1/8" — 1" ID
1/8" — 3/4" ID
Process flexibility
As needed, with no pre-defined location
Pre-designed in SU assembly
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* Requires initial capital expenditure** Requires a small hand tool
The Biosealer® TC is an automated sealer for aseptic disconnection of thermoplastic tubing. This innovative technology allows sterile disconnection of dry or liquid-filled TPE tubing from 1/4" to 1" outer diameter. The Biosealer® TC seals TPE tubes by thermally bonding the tubing, ensuring a high level of stability for sterile disconnection.
Explore Biosealer® TC
The Clipster® range of disconnectors allows fast and reliable aseptic disconnection in biopharmaceutical manufacturing operations. Its unique design allows unplanned disconnections at the point of use.
Explore Clipster®
Quickseal® disconnection is a simple one-step cut technology to form an aseptic seal. Quickseal® collars are pre-installed on silicone or thermoplastic elastomer tubes, giving clear instructions where to cut.
Explore Quickseal®
Learn about the importance of building disconnection technology redundancies into the biopharmaceutical manufacturing process to mitigate risks and disruptions.
Read More
Benefit from low extractable profiles for both silicone and TPE tubing to transfer critical fluids across process steps.
Sartorius brings together multiple technologies and vast experience, with more than 1.2 million sterile connections supplied every year, we can help y...
The Biowelder® TC is an automated device for connecting thermoplastic tubing in a sterile welding operation.
Opta® SFT aseptic tube connectors allow fast and reliable sterile connection and fluid transfer between two pre-sterilized process components.
A comprehensive portfolio of standard and custom tube sets for transfer, distribution or filling of in-process fluids.
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