Engineered for Ultimate Upstream Performance
Biostat STR® single-use bioreactors and the Biobrain® automation platform offer multiple configurations and convenient software upgrades to quickly adapt facilities as requirements change. The Generation 3 system is now available with integrated Repligen XCell ATF® Technology for intensified processes and access to our best-in-class BioPAT® toolbox. Biostat STR® bioreactors and Flexsafe STR® bags range from 50 L to 2,000 L and can enhance speed, quality, and flexibility in process development and commercial manufacturing operations.
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Scalability from benchtop to production scale through conventional design & geometric similarity with working volume range from 12.5 L to 2,000 L.
Achieve superior cell viability, cell density and increased product purity and lower the risk of batch loss or inconsistencies.
One system provides all the flexibility needed for numerous modalities, from mAbs and biosimilars to pDNA, mRNA, and vaccines.
The Biostat STR®️ Generation 3 single-use bioreactors are engineered for ultimate upstream performance. Available with integrated Repligen XCell® ATF Technology for intensified processes, the system simplifies process set-up and operation while eliminating the need for separate control hardware.
Empowered rapid product development and seamless scaling to commercial manufacturing with Biostat STR®.
Outstanding speed, quality, productivity, and seamless integration into existing automation infrastructure with Biostat STR®.
The Biostat STR® Generation 3 systems serve all process strategies, from classical batch to intensified processes, and cover all stages of the seed train up to the final production bioreactor with a working volume range from 12.5 L to 2,000 L.
The Biostat STR® 3 enables seamless scaling from Ambr® 250 up to 2,000 L based on conserved geometry and supported by BioPAT® Process Insights software.
Get your Flexsafe STR® bags in time for your next run.
Bioreactor bags are the single-use equivalent to stainless steel vessels - the actual chamber where the cell culture is placed. They are ususally provided sterile and ready to use following installation in the bag holder. A bioreactor bag is typically equipped with all necessary connections and lines for gassing, media feeds and sampling. Sensor probes for process analytical technologies can either be inserted through specific ports or are directly included in the bag assembly as single-use sensors.
As bioreactor bags are made from plastic, careful considerations of extractable and leachables (E&L) are needed. Sartorius has full control of its propietary range of Flexsafe film material from resin formulation up to bioreactor bag assembly and can thus provide consistent quality and comprehensive E&L data.
Single-use bioreactors are available in a range of volumes, starting as low as 10 mL of working volume up to several thousand liter capacity. Thus, single-use bioreactors can be used in all applications from research to process development, pilot and clinical scale and ultimately, commercial manufacturing.
STR stands for stirred-tank reactor. It describes a bioreactor type where mixing is achieved through a central stirrer element inside the culture vessel. STR type bioreactors are available as stainless steel and single-use equipment. They are well known for excellent scalability, as constant height to diameter ratios and vessel diameter to impeller diameter ratios can be achieved.
We at Sartorius often refer to our Biostat STR® single-use bioreactors as STR, because these bring all the benefits of traditional stirred-tank reactors in a user friendly single-use system.
Discover the unrivaled modular, perfusion-enabled seed train concept featuring the Biostat® RM and a seamless seed transfer t...
In this webinar, Sartorius experts present the latest PI technologies, including advanced Biostat® bioreactors integrated with PAT functionality controlled by the Biobrain® automation platform.
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