Commercial Scale Freeze/Thaw Solutions
Safe, Reliable and Adaptive Frozen Transfer Solutions
Building on more than 15 years’ experience in designing freeze and thaw solutions, Sartorius offers lab-scale and production-scale solutions for every process step when frozen storage and frozen shipment are required. This allows biopharmaceutical manufacturers to effectively decouple downstream process steps and securely transport drug substances to drug product sites. With options that accommodate blast, horizontal and vertical plate freezers, the Celsius® platform offers an end-to-end, integrated approach that enables monitoring and controls to assure product quality and integrity at scale.
Safely and confidently manage the entire cold chain, from filling and freezing to shipping, thawing and dispensing.
Flexible implementation according to product and process needs
Unparalleled supply reliability based on control of manufacturing processes and global production operations.
A system built on purpose-driven design to reduce manual handling of drug substance and minimize/prevent risk of cryoconcentration.
Up to 25% of vaccines are believed to be lost due to cold chain failures. Learn how Celsius® FFT and FFTp containers prevent losses.
Sartorius offers fully integrated, end-to-end freezing solutions, as well as the flexibility to introduce quality freezing containers into existing freeze/thaw operations and infrastructure. Explore freezing storage and shipping solutions based on infrastructure or product needs.
Attribute
Celsius® CFT
Celsius® FFT
Celsius® FFTp
Platform
Complete platform
Container plus shippers
Freezer type
Vertical plate freezer
Conventional and blast freezer
Horizontal plate freezer
Controlled freeze/thaw
Yes
Possible in blast freezer
Load capacity
100L per thermal cycle
Depending on freezer type
200L per thermal cycle
Container range
1L – 16.6L
2L – 12L
6L – 12L
Explore Celsius® FFT
Explore Celsius® FFTp
Celsius® CFT (Controlled Freeze and Thaw) is a fully integrated, end-to-end freeze/thaw solution that reduces risk by minimizing the handling of drug substance, while a controlled-rate plate freezing and thawing system minimizes cryoconcentration.
Proven performance to -80°C
Complete solution from filling through draining
A robust and reliable platform for cGMP manufacturing
Explore Celsius® CFT
Celsius® FFT (Flexible Freeze and Thaw) is a sterile, pre-assembled, ready-to-use freeze container with a unique bag-in-shell system that works seamlessly in any conventional or blast freezer.
Leveraging existing freezer infrastructure
Bulk processing with versatile multi-modal shipping solutions
Celsius® FFTp (Flexible Freeze and Thaw for Plate Freezer) offers the unique bag-in-shell system, but with a flatter, more compact design to fit perfectly against the surface of a horizontal plate freezer.
Fast and reproducible thermal cycling
Purpose-designed box shippers
AliquoT® automates drug substance distribution to Celsius® containers with high accuracy and cost savings without the risk of tolerance breach.
Explore AliquoT®
Building on more than 15 years of expertise in freeze/thaw solutions, Sartorius offers frozen storage and shipping solutions to meet the challenges of the biopharmaceutical cold chain. With global operations and an extensive network of engineers and industry experts, Sartorius provides the technology, expertise and support manufacturers need to succeed.
What are the practical implications of Annex 1 specifically for cold chain management?
Secure fluid integrity during handling and shipping with robust pre-designed solutions.
Please select your country so we can show you products that are available for you.
The content of our website is always available in English and partly in other languages. Choose your preferred language and we will show you the content in that language, if available.
Shop Sartorius Products Now