High Performance Liquid Chromatography Systems
From Clinical to Commercial Manufacturing
As the drug pipelines become more diverse with complex and multiple products, these drive new manufacturing requirements. For instance,
The Hipersep® Flowdrive Platform is a family of preparative HPLC systems designed for the purification of peptides, oligonucleotides, insulin and other small molecules.
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The Hipersep® Flowdrive Platform offers highly sophisticated, easy-to-use equipment with a unique, compact design controlled by the Hipersep® SC software.
Hipersep® Flowdrive Process M
Hipersep® Flowdrive L
Scale
Clinical Manufacturing
Clinical / Commercial Manufacturing
Commercial Manufacturing
Flow Rate Range
6-90 L/hr
60-500 L/hr or20-200 L/hr (Low Flow Version)
300-1000 L/hr
500-1600 L/hr
1000-2500 L/hr
Max Pressure
100 bars
70 bars
Typical Column Diameter
50/80/110/150 mm
110/150/200/300/450 mm
450/590 mm
590/800 mm
800/1000 mm
Certification and Explosion Proof
CE certification with optional ATEX Zone 2UL certification with optional Class I Division 2
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The Hipersep® Flowdrive Pilot is a modular, compact and ergonomic system designed to minimize cross-contamination risk.
The Hipersep® Flowdrive Process M is an innovative system with a pressure capacity of up to 100 bars and is compatible with high-temperature purification processes (up to 85°C), allowing for unmatched performance levels while meeting the stringent requirements of new pharmaceutical applications such as oligonucleotides.
The Hipersep® Varicol is a multi-column, continuous chromatography concept particularly well-suited to large-scale separation of binary mixtures (e.g., enantiomers) and fractionation of other complex mixtures. This technology is designed to adapt seamlessly to users’ specific process requirements with guaranteed and repeatable performance.
Our columns meet high design standards, thus ensuring efficiency and scalability. DAC technology enables reproducibility and robustness over time.
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Contribution of preparative HPLC in manufacturing, from small molecules to biologics
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