Microbial Bioreactors & Fermenters | Sartorius

Microbial Bioreactors and Fermenters

The Biostat STR® Microbial, a single-use (SU) fermenter engineered for microbial applications, combines the advantages of SU with the performance of stainless-steel. It allows fast batch-to-batch turnover for high productivity and has a compact footprint. The Biobrain® automation platform supports stand-alone GMP tools and precise control. With working volumes up to 40 L, the Biostat STR® Microbial is ideal for developing and manufacturing high value products including pDNA, fAbs, recombinant proteins and vaccines.

Gain Robust Performance Similar to Stainless-Steel Systems

Achieve high growth rates, an OD600 of >300, a kLa of 675 1/h, stirring speeds at 500 rpm, efficient cooling, and high gas flow at (1.5vvm).

Increase Productivity and Project Throughput

Accelerate batch-to-batch turnover with a single-use design and ready-to-use Flexsafe STR® bags that negate extensive cleaning protocols.

Control and Automate Your Processes With Biobrain®

Gain advanced process automation and control of cultivation parameters with a proven GMP-ready system that integrates with your DCS.

Stay Flexible with a Modular Design and Setup

Save space with a versatile system that can acaccommodate either cell culture or microbial bag holders.

Engineered for Fermentation Processes

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Engineered for Robustness and Speed

Designed for robust and easy process transfer and scaling of challenging microbial applications. Proven excellent performance KPIs of OD600 300, kLa1 of 675 1/h, and a specific growth rate of 0.15ℎ^ (−1) in E. coli cultivations.

  • Develop your E. coli processes within shorter timelines
  • Establish small-scale CM with increasing productivity
  • Simple to install and flexible
  • Ease processing through GMP-ready automation

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Engineered for Seamless Process Transfer

Easy, unrestricted conversion from established stainless steel processes. Coupled with single-use Flexsafe® STR bags, allows easier waste disposal and reduction of contamination and operator risk.

  • Faster setup through Biobrain® GMP stand-alone capability
  • Run more projects per time through higher batch-to-batch turnover
  • Lower footprint, lesser installation time, and pipping

Featured Assets

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Application Note

A Novel Fermenter for High Cell Density Microbial Cultures  

Evaluation of the Biostat STR® microbial bioreactor in a high cell density E. coli exponential fed-batch cultivation.

Article

Proven Superior Performance

Read a study that compares E-coli processes in the Biostat® STR with processes in stainless steel bioreactors.

Related Assets

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Poster

Biostat STR® Microbial for Highly Demanding Fermentation Processes

PDF 2.1 MB
Poster

Evaluation of a Stirred Small Scale Single-Use Bioreactor for Microbia...

PDF 2.3 MB
Poster

Unveiling Process Solutions For Plasmid DNA Fermentation Across Upstre...

PDF 2.4 MB

Consult Our Experts

Consult Our Experts

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