Imagine Removing the Capture Bottleneck
Re-Imagine Chromatography with Sartobind® Rapid A
Imagine Up to 5x More Productivity
Re-Imagine Chromatography with Resolute® BioSMB
Imagine Up to 80% Lower Resin Volume and Costs
Imagine Performing Four Steps on a Single System
Re-Imagine Chromatography with Resolute® BioSC
Chromatography is the workhorse of downstream bioprocesses, but capture chromatography is one of the most expensive and rate-limiting steps. Low flow rates extend the processing time and limit the productivity of downstream production. Non-value-added activities – such as column packing and system cleaning – also strain resources and increase risk, operational area, and footprint.
These chromatography challenges create broad opportunities for improving efficiency during downstream processes. It is time for the industry to collectively re-imagine chromatography to overcome these obstacles.
The industry is on the cusp of a paradigm shift in chromatography. By embracing more effective technologies and adopting process intensification strategies, you can pioneer these innovations and establish next-generation, streamlined purification processes.
Explore our range of systems specifically designed for intensification and chromatography media to start building an efficient downstream process tailored to your needs.
Downstream process intensification increases productivity and flexibility while decreasing COGs and timelines. Yet, knowing how to integrate strategies into your process can pose a challenge. Whether you want to boost the productivity of your capture step or intensify your entire downstream process. Find a system suitable for your purification needs.
Explore Our Sartobind® Membrane Toolbox
Explore Resolute® BioSMB
Explore Resolute® BioSC
Next-generation therapies typically rely on large particles such as nucleic acids, viral particles, and exosomes. These biomolecules challenge conventional chromatography techniques, which struggle to quickly yield high recoveries while also maintaining the required purity.
Adapt to the challenges of evolving therapeutics with next-generation solutions designed for the purification of large biomolecules.
Explore CIM® Monolithic Columns
Are you ready to re-imagine your chromatography workflow? Membranes have an open structure that supports faster flow rates, accelerating process timelines and lowering the cost of goods.
Sartobind® Rapid A has several benefits compared to Protein A resins:
Our broader Sartobind® Membrane toolbox covers the entire workflow and offers up to 30x productivity gain during polishing in flowthrough mode.
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Are you ready to re-imagine your chromatography workflow? Multi-column chromatography supports better resin utilization, meaning considerable savings, especially at the affinity capture step.
Intensify your capture chromatography with the Resolute® BioSMB multi-column chromatography system:
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Are you ready to re-imagine your entire downstream process? Our multi-step chromatography solutions support the connected and continuous operation of multiple steps on a single system.
Intensify your downstream workflow with the Resolute® BioSC multi-step chromatography system.
Are you ready to re-imagine large biomolecule purification? Our chromatography monoliths are ideal for the purification of molecules commonly used in next-generation therapies (such as mRNA and viral particles).
Enhance the purification of your new modalities with CIM® monolithic chromatography.
Chromatography Resins
Monolithic Chromatography
Chromatography Membranes
Automated Columns
Manual Columns
Pre-Packed Columns
Preparative HPLC Columns
Intensified and Continuous Chromatography
Multi-Use Batch Chromatography Systems
Single-Use Batch Chromatography Systems
Preparative HPLC Chromatography Systems
Learn how to build efficient, connected downstream processes with our white paper.
Connecting & intensifying your mAbs processing can improve productivity. See an example in action in this ondemand webinar.
Learn how chromatography membranes offer advantages over protein A resins.
MCC can help you improve efficiency while achieving your desired QTPP. Learn what to consider when transitioning from single to multi-column chromatography.
It’s time to be practical about productivity in chromatography. Find out how to make your mAb capture more productive, and the additional benefits of switching from resins to membranes.
Demand for higher output and flexible manufacturing of mAbs requires new solutions. Membrane chromatography offers several key advantages over columns for highly productive and scalable processes.
Sartorius’ global manufacturing facilities fully meet the highest quality standards and consistently supply powder and liquid buffers
The Fast, Flexible, and Intelligent Single-Use Mixer for All Mixing Steps in cGMP Bioprocessing. Mix Smarter - Not Harder.
Secure fluid integrity during handling and shipping with robust pre-designed solutions.
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