Sartoclear® Depth Filter | Sartorius

Sartoclear® Depth Filters

Sartoclear® Depth Filters

Always the Best Solution for Your Harvest

Sartoclear® Depth Filters are cellulose-based filters developed for demanding clarification applications in the pharmaceutical and biopharmaceutical industry. The wide range of grades offers a solution for a variety of applications such as post centrifuge clarification and post perfusion filtration or direct bioreactor harvest.


Sartoclear® Depth Filter application areas

  • Mammalian cell culture harvests
  • Microbial lysates
  • Removal of precipitates from sera and plasma
  • Particle and colloid removal from process intermediates
  • Media filtration
  • Viral vectors (AAV; Adeno-associated virus)

Product Overview

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Sartoclear® Caps

Sartoclear® Caps are easy-to-use screening devices that help you to find the best grade for your application.

Sartoclear® Midscale Cassettes

Sartoclear® Depth Filter Midscale Cassettes are developed for scale-up filtrations and small-scale processing with volumes between five to 10 liters.

Sartoclear® Depth Filter Cassettes

Three different sizes of Sartoclear® Depth Filter Cassettes allow for a seamless adaptation to different process fluid volumes.

Sartoclear® Depth Filter Modules

Sartoclear® Depth Filter modules are stackable, lenticular shaped depth filters for use in stainless steel housings.

Find The Optimal Grade for Your Application

Sartoclear® DL-Series are high capacity depth filters made of two distinct filtration layers. The primary coarser layer is followed by a second finer layer which enables the removal of a broader spectrum of particles in a single step.

The Sartoclear® DL-Series are pre-selected and optimized to serve the most common biopharmaceutical applications.

Grade

Description

Primary 
Clarification


DL90

Primary (coarse) clarification.

DL75

Primary clarification.
In case of AAV clarification can serve as single-stage clarification solution directly followed by a sterile filter.

Primary | Secondary 
Clarification

DL60

Primary or secondary clarification. In certain cases also serves as a single-stage clarification solution directly followed by a sterile filter (e.g. AAV clarification).


Secondary Clarification

DL20

Secondary clarification post-depth filtration, -centrifuge or -perfusion.

DL10

Secondary clarification post depth filtration or centrifuge.

System Overview of Sartoclear® Depth Filters

Maximize Product Recovery

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  • Manifold set comes with pre-installed tubing on vents and drains
  • Tubing with quick connectors at the end can be hooked up with pressurized air or bags
  • Retained medium is recovered through controlled air pressure

Practical Design for Easy Cassette Exchange

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Holding grooves allow the user to take each cassette out step-by-step.

Rounded bottoms enable the user to take out used cassettes in an ergonomic way.

Handles enable comfortable carrying with both arms.

Sartoclear® Depth Filters are a full linear scalable solution for cell broth filtration with cell densities <15 × 10 Mio/mL, from process development to commercial manufacturing.

Sartoclear® Depth Filters are available in a variety of formats to serve you from the first steps, throughout clinical phases, and up to large-scale manufacturing while always keeping the same filter material.

  • Sartoclear® Depth Filter caps are easy-to-use screening devices that help you to find the best grade for your application. All packages contain three units of the same grade and come with plug-in Luer adapters for the easiest possible exchange of filters.
  • Sartoclear® Depth Filter midscale cassettes are developed for scale-up filtrations with volumes between 5 to 10 liters (depending on the cell density). They are designed in gradient shape for mechanical reinforcement to meet the application conditions.
  • Sartoclear® Depth Filter cassettes are single-use filtration devices specially designed for biopharmaceutical clarification applications. The modular devices provide linear scalability from small- to large-scale processes. Three different sizes of filter holders allow for seamless adaptation to different process fluid volumes.

Learn more about Sartoclear® Depth Filters

Datasheet

Sartoclear® Depth Filter - Cell Clarification and Contaminant Removal Technologies

PDF | 674.0 KB
Datasheet

Positioning Sheet: Cell Clarification Technologies Matrix

PDF | 585.4 KB
Datasheet

Filter Holders - For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers

PDF | 976.1 KB
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Ksep® Systems

The kSep® system is a single-use centrifuge used for cell harvest. Learn more about this automated, fully closed system.

Consult Our Experts

Consult Our Experts

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Laboratory Weighing Services

You Can Count on Our Support

Trust our comprehensive range of services for your Bioprocess: We gladly assist you with tasks like system installation, process optimization and many...

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