Octet® SPR Sensor Chips and Consumables | Sartorius

Octet® SPR Sensor Chips and Consumables

Sensor chip selection is a critical feature of every Surface Plasmon Resonance (SPR) assay. From initial design and development to data acquisition and analysis, overall data integrity is influenced by initial sensor chip selection.

Each Octet® SPR sensor chip has been specifically designed to allow generation of robust and reproducible results for every application – from large molecules, molecular complexes, viruses or whole cells, to small molecules or antibody fragments.

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Quickly find Octet® SPR products by searching by category or filtering by attributes.

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Discover Octet® SPR with unique patented injection modes

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Explore Octet® SPR Sensor Chips and Consumables

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Octet SPR Vials

Octet® SPR Sample and Reagent Vials

A full range of sample and reagent vials, including 0.9 mL, 2 mL and 7.5 mL volumes.

Octet SF3 Plate Adapter

Octet® SPR Sample Rack Adapters

Choose from either 96 or 384 well sample rack adapters, each ranging from 120 µL to 1 mL volumes.

Octet SF3 Rack Seal

Octet® SPR Microfoils

Generate reproducible results over extended run-times by minimizing reagent evaporation.

Octet SF3 OQ Reagent

Octet® SPR OQ, IQOQ and PMOQ Services

Ensure total confidence through Operational Qualification to provide documented evidence of platform performance.

Octet SF3 Maintenance Kit

Octet® SPR Maintenance Kit

Remove absorbed materials from the system during weekly clean, desorb and decontamination protocols to ensure long-term performance.

Octet SPR Maintenance Chip

Octet® SPR Maintenance Chip

Developed for use during all cleaning protocols to ensure the system is maintained in excellent working order to maximize run-time.

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Features of the Sartorius Octet® SPR Range

Octet® SF3 SPR
Octet® SF3 SPR
Octet SF3 Maintenance Kit
Robust and Reliable
  • Exceptional sensitivity for small and large molecules, low baseline noise and drift, large injection volumes and novel OneStep® and NeXtStep™ Gradient Injection Technologies
  • Generate high-quality kinetics and affinity data in a fraction of the time compared to standard multi-cycle kinetics

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Accurate and Reproducible
  • Each Octet® SPR sensor chip can be classified according to its immobilization matrix, binding capacity or type of bond formed with the ligand
  • Irrespective of classification, each Octet® SPR sensor chip can help facilitate the generation of highly accurate and reproducible results across a variety of molecules and analyte complexes

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Confidence and Maintenance
  • Ensure total confidence in all results generated using the Octet® SF3 SPR platform 
  • Operational Qualification (OQ) provides documented evidence of platform performance
  • The Octet® SPR Maintenance Reagent kit helps remove any absorbed proteins or other materials from the system and ensures long-term instrument performance

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Explore the SPR Sensor Chips Collection

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Octet® SPR COOH1 Sensor Chips

  • Low binding capacity
  • Matrix length from gold surface: ~2 nm
  • Minimal distance between analyte and planar surface results in highly sensitive interactions
  • Useful for large molecular weight analytes due to its matrix-free surface
  • Can be used for whole cell, virus particle, multivalent or large analyte assays


Buy Octet® SPR COOH1 Sensor Chips

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Octet® SPR PCH Sensor Chips

  • Highest capacity surface of all Octet® SPR sensor chips
  • Matrix length from gold surface: 150 nm
  • Useful for small molecules, fragments, organic molecules and low molecular weight compounds
  • Can be used in experimental conditions not favorable to dextran polycarbonate surfaces


Buy Octet® SPR PCH Sensor Chips

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Octet® SPR CDL Sensor Chips

  • Medium binding capacity
  • Matrix length from gold surface: 50 nm
  • Short dextran matrix
  • Minimal distance between analyte and planar surface results in a highly sensitive interaction
  • Intermediate (>1 kDa) - large (>25 kDa) molecules 
  • Can be used for whole cell or virus particle work


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Octet® SPR CDH Sensor Chips

  • High binding capacity
  • Produces a highly stable covalent bond
  • Matrix length from gold surface: 150 nm
  • Small molecules: fragments and organic compounds
  • Large molecules, viruses and proteins
  • Biocompatible with a wide range of molecules


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Octet® SPR Streptavidin Sensor Chips

  • Medium to high binding capacity
  • Senor chip surface has a lower electrostatic charge compared to amine sensors
  • Intermediate (>1 kDa) - large (>25 kDa) molecules
  • Controlled ligand orientation facilitates optimal analyte capture with low interference of the target ligand
  • Validated for a broad range of applications


Buy Octet® SPR SADH Sensor Chips

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Octet® SPR HisCap Sensor Chips

  • High binding capacity
  • Suitable alternative for proteins not amenable to amine coupling
  • Small molecule, peptide or fragment kinetics
  • Stable baseline, important for accurate kinetic analysis


Buy Octet® SPR HisCap Sensor Chips

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Octet® Surface Plasmon Resonance Resources

Octet® SPR Downloads and Guides

Find the latest guides, application notes, white papers and more for the next generation Octet® SF3 Surface Plasmon Resonance (SPR) platform.
 

Brochure

Octet SF3 Instrument Brochure

PDF | 4.8 MB
Brochure

Octet® SPR Sensor Chips

PDF | 1.3 MB
Brochure

Octet® SF3 SPR Service Plans

PDF | 2.5 MB
Brochure

Octet SF3 Pulse Injection - Brochure | Sartorius

PDF | 1.7 MB
Octet SF3 SPR Flyer cover
Flyer

Octet® SF3 SPR Instrument

PDF | 468.7 KB
Flyer

Octet® SF3 Consumables

PDF | 411.3 KB
Flyer

Octet® SF3 SPR Maintenance

PDF | 601.7 KB
The Next Generation of SPR-Based Interaction Analysis cover
Flyer

The Next Generation SPR-Based Interaction Analysis

PDF | 273.6 KB
Flyer

Octet® SPR Sensor Chip Selection Guide

PDF | 591.8 KB

Best Practice Guide: Octet® SF3 Assay Orientation

PDF | 940.3 KB

Best Practice Guide: Minimize Artifacts 

PDF | 861.4 KB

Best Practice Guide: Octet® SF3 System Maintenance

PDF | 187.3 KB

Best Practice Guide: Minimizing the Effects of Non-Specific Binding

PDF | 120.0 KB

Best Practice Guide: Double Reference Subtraction

PDF | 868.5 KB
Best Practice Guide: Octet SPR Sensor Chip Preparation

Best Practice: Octet® SPR Sensor Chip Preparation

PDF | 99.2 KB
Octet SPR Analysis User Guide
User Guide

Octet® SPR Analysis User Guide

PDF | 2.5 MB
Octet SPR Discovery Software User Guide
User Guide

Octet® SPR Discovery Software User Guide

PDF | 7.6 MB

User Guides

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Octet SPR Analysis User Guide
User Guide

Octet® SPR Analysis User Guide

PDF 2.5 MB
Octet SPR Discovery Software User Guide
User Guide

Octet® SPR Discovery Software User Guide

PDF 7.6 MB

Application Notes

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Application Note

Beyond Sensitivity: The Power of In-Line Mixing for Competitive Compou...

Competitive compound analysis in drug discovery with novel gradient injections to determine the site specificity of small molecules.

application note thumbnail
Application Note

Kinetics Determination of High Affinity Molecular Interactions Us...

PDF 212.2 KB
Application Note

Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity...

PDF 289.9 KB
SPR Fragment based drug discovery
Application Note

Fragment-Based Drug Discovery (FBDD) Using Octet® SPR OneStep® and NeX...

PDF 5.1 MB
OneStep lead characterization of high affinity biologic interactions
Application Note

OneStep® Lead Characterization of High Affinity Biologic Interactions

PDF 2.2 MB
Application Note

Recovery of Sample Using the Octet® SF3 - Application Note | Sartorius

PDF 1.4 MB

Guidelines for OneStep®️ Assay Design

PDF | 3.4 MB

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