Tuflux® Tubing
Liquid transfer is an essential part of biomanufacturing processes. With Tuflux® tubing, benefit from low extractable profiles for both silicone and TPE tubing to transfer critical fluids across all process steps.
Tuflux® tubes are available in standard dimensions from 1/8" (3.2 mm) to 1" (25.4 mm) for the internal dimensions and a wall thickness from 1.6 mm to 4.8 mm. These tubes’ function both as non-sterile standalone coils to build your own assemblies and as part of pre-sterilized single-use systems from Sartorius, which include bags, transfer sets, filters, or bioreactors.
There are three types of Tuflux® tubes, the table below will help you assess which one is best suited for your process need:
Attributes
Tuflux® SIL Braided
Sealable | weldable
No
Yes
Recommended for pumping
Yes*
Recommended for high pressure
Standard dimensions available from stock (IDxOD)
1/8" x 1/4" (3.2 x 6.4 mm)1/4" x 3/8" (6.4 x 9.5 mm)1/4" x 7/16" (6.4 x 11.1 mm)3/8" x 5/8" (9.5 x 15.9 mm)1/2" x 3/4" (12.7 x 19.1 mm)3/4" x 1" (19.1 x 25.4 mm)3/4" x 1-1/8" (19.1 x 28.6 mm)
1/8" x 0.355"(3.2 x 9 mm)1/4" x 1/2" (6.4 x 12.7 mm)3/8" x 5/8"(9.5 x 15.9 mm)1/2" x 7/8"(12.7 x 19.1 mm)3/4" x 1-1/8"(19.1 x 28.6 mm)1" x 1-3/8"(25.4 x 34.9 mm)
Extractable guide | validation guide
Yes | Yes
Dimensional color coding
Yes (YL, OR, RD, WH, GY, BL, BK)
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*for light pumping applications
Tuflux® SIL is designed to facilitate fluid transfer in biopharmaceutical manufacturing processes. Tuflux® SIL is a highly resistant platinum-cured silicone tubing manufactured by Raumedic.
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Benefit from a silicone tubing with a low extractable profile for the transfer of critical fluids. Sartorius’ platinum-cured silicone tubing undergoes an extensive post-curing process after extrusion to create a product with extremely low levels of siloxanes, the most relevant extractable group within silicone products. Tuflux® SIL tubing is manufactured in ISO 7 cleanrooms to maintain the cleanliness of the drug substances it carries.
Tuflux® SIL tubing's hardness of 60 Shore A combined with an optimized wall thickness dedicated per size ensures a solid compromise between pressure resistance and long pump life with high flow rates. Tuflux® SIL has been designed to prevent kinking but maintain enough flexibility for efficient operator handling.
Tuflux® SIL undergoes a surface treatment in a plasma process that reduces the stickiness of the surface when compared to non-surface treated silicone tubing products. This eases the unwinding of coils, as well as handling in general.
Tuflux® TPE has been designed specifically for liquid transfer in the biopharmaceutical industry. It can be heat sealed and welded with Biosealer® TC and Biowelder® TC to maintain sterile conditions.
The unique color-coding of Tuflux® TPE tubing aligns with the Biowelder® TC tube holders. In addition, the printing of the inner and outer diameter dimensions, as well as the tube material, facilitates identification and ease of use and mitigates operator errors.
Tuflux® TPE has been specifically designed to be compatible with cell growth. Indeed, its antioxidant levels have been optimized in order to prevent any risk of toxicity caused by the presence of bis(2,4-di-tert-butylphenlyl) phosphate (bDtBPP). As a result, cell growth is not inhibited even under worst-case surface-to-volume ratios in small-scale applications.
Co-welding between Tuflux® TPE and different TPE tubes is possible thanks to Biowelder® TC. Indeed co-welding parameters have been validated for different combinations of gamma-irradiated and/or autoclaved tubes.
Braided Tuflux® SIL is the newest product in the Sartorius tubing portfolio. Its composition is identical to Tuflux® SIL just with an integrated mesh.
Braided Tuflux® SIL is made of the same silicone as Tuflux® SIL and therefore benefits from the same advantages: low extractable profiles, a good compromise between strength and flexibility and a low tack treatment to reduce surface stickiness. It is reinforced with a mesh, enabling it to be resistant to pressures up to 60 bar.
Braided Tuflux® SIL is reinforced with a medical grade PET mesh material which enables high pressure resistance while ensuring that your fluids are kept safe.
Biowelder® Total Containment (TC) and Biosealer® TC provide innovative solutions to complement your Tuflux® TPE system.
The Biowelder® TC is an automated device for connecting thermoplastic tubing in a sterile welding operation.
The Biosealer® TC is a robust, flexible and easy-to-use device that generates sterile TPE tubing disconnections.
Tubing assemblies from Sartorius enable flexibility in all process steps. Select a predesigned single-use tubing set or configure a custom design from an extensive component library.
Benefit from low extractable profiles for both silicone and TPE tubing to transfer critical fluids across process steps.
Clipster® is a single-use solution for disconnecting tubing at any stage in the process while maintaining sterility.
Opta® SFT aseptic tube connectors allow fast and reliable sterile connection and fluid transfer between two pre-sterilized process components.
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