Streptavidin is often deployed as the molecule of choice for covalent linking to solid surfaces for ligand binding assays applications. Streptavidin’s biophysical properties enables it to form a high affinity non-covalent bond with biotin allowing for the tight immobilization of biotinylated ligands.
Octet® High Precision Streptavidin 2.0 (SAX2) Biosensors are developed to be used with the Octet® Bio-Layer Interferometry (BLI) platform and are qualified for applications in downstream drug discovery and regulated environments. They are QC-tested to meet precision-controlled biotinylated-ligand loading coefficient of variation (CV) specification of <4% within a lot and CV range of 20% across different lots and can used with any biotinylated molecule for both kinetics and quantitation assays where stringent precision requirements are in place.
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