Alone but Not Lonely: Designing an Outgrowth-Promoting Environment for Single Cell Cloning
Watch time: 58 minutes
Doing things quickly has become a paradigm in biopharma development. Simultaneously, in early development, variability is required to extract the most data and increase chances of success. This leads to a demand in high-throughput, automated techniques, and highly skilled professionals. Risk taking and early adoption of new techniques is part of innovation to optimize workflows, especially when projects are highly individual and cannot follow standard routines. In clone development, this includes working with very different host cell lines, customized protocols, and unforeseen circumstances which needs adaptable processes and multifunctional devices.In this webinar, Vicky Goralczyk and Lena Thoring of FyoniBio demonstrate how the CellCelector platform can effectively be used for cell line development, host cell engineering, and cell adaptation and how it was successfully integrated into FyoniBio‘s platform for development of biopharmaceutics for autologous and allogeneic cell therapies.
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Director of Cell Line Development and Bioprocess DevelopmentFyoniBio GmbH
Vicky has a doctoral thesis on development of a perfusion bioreactor for cells grown on ceramics at Berlin University of Technology.
She then deepened her business knowledge for five years as a product manager for fertility products. Since 2022, Vicky has been the Director of Cell Line and Bioprocess Development at FyoniBio GmbH.
Lena has a doctoral thesis on development of alternative protein production systems based on CHO cell lysates, gained at the Berlin University of Technology.
This was followed by two years at Fraunhofer IZI-BB managing diverse research and customer projects related to production of difficult-to-express proteins.
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