Application Note: Facilitating Rapid and Accurate Cell Line Development

Overview

Generating biologics often requires development of cell lines capable of producing the molecule of interest. Manufacturing a cell line that can be successfully cultured, is robust, and produces the biotherapeutic required at a high enough yield are all key components to a successful cell line development (CLD) workflow.

CLD techniques, such as limiting dilution (LD), traditionally require large quantities of reagents and consumables to achieve single cell seeding as required to create new cell lines. CellCelector Flex mitigates this issue by monitoring clones and ensuring monoclonality from the outset. This application note outlines the utility and value of the CellCelector Flex at key stages of the cell-line development workflow.

• Document type: Application Note
• Page count: 8
• Read time: 12 minutes

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