Concentration Response Curves or EC50/IC50, are mechanisms to study the effectiveness of a drug under various conditions.
Studies such as NK cell-related immunotherapeutics, for the treatment of cancers, can benefit from the use of concentration response curves.
This video sequence reveals the ease of creation and review, of dose responses using iQue Forecyt® Software and data from the iQue® Human NK Cell Killing Kit. Expression of NK cell phenotypic markers, target cell killing and effector protein secretion, are measured to discern differences in ADCC potency between monoclonal antibodies, and to also provide insight into potential treatment efficacy across donors.
Simultaneous, high throughput analysis of target cell killing, NK cell phenotypic and activation marker expression, and quantification of secreted eff...
iQue Forecyt® Software provides plate level annotation, analytics, and results visualization tools not found in traditional flow-based analysis softwa...
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