Technology Digest: Mitigating Cell Culture Variability With Robust Screening of Raw Materials

To meet GMP Guidelines, cell and gene therapies must have consistent cell cultures. Consistency is achieved by the following:

• Screening raw materials and eliminating the risks of cross-contamination and bacterial and viral contamination
• Full consideration should be given to early process development to avoid variation further down the line
• The use of automation and turn-key processes
• Reliable raw materials inputs