The cell line development group at Biogen IDEC needed a robust assay for the measurement of Fc-fusion protein (Protein 1) in crude cell culture supernatants. The group had historically used HPLC for protein quantitation during screening and selection of promising mammalian clones at every scale-up step, from 96- well microplates to 3L-bioreactors. They wanted to replace the HPLC method due to its low throughput, cumbersome sample processing, and long run times with a higher-throughput alternative that provided accurate, reliable results.
Download the application note to learn more.
Please select your country so we can show you products that are available for you.
The content of our website is always available in English and partly in other languages. Choose your preferred language and we will show you the content in that language, if available.
Shop Sartorius Products Now