Utilizing Advanced Cell Models to Investigate Neurological Diseases and find Potential Therapies eBook| Sartorius

eBook: Utilizing Advanced Cell Models to Investigate Neurological Diseases

Last updated: November 2023

Overview

The complexity of neurological diseases, which encompass neurodegenerative and developmental diseases, as well as neuro-oncology, necessitates a comprehensive, multidisciplinary approach for both diagnosis and management. Current research is tirelessly working towards uncovering the root causes of these diseases and formulating innovative treatment methods. The potential for improved patient outcomes and enhanced quality of life lies in early diagnosis, a deeper comprehension of disease mechanisms, and progress in therapeutic interventions.

This eBook presents a comprehensive analysis of advanced cell models, such as primary or iPSC-derived cell types, and their significance in neurological disease research. It emphasizes the importance of non-perturbing analysis in understanding the development, progression, and treatment of these diseases. Explore the use of live-cell imaging as a robust tool for temporally investigating cellular changes in 2D or 3D without further influences. The methods and applications presented aim to educate researchers on new technologies and techniques for analyzing in vitro cell models.


  • Document type: eBook
  • Page count: 49
  • Read time: 60 minutes


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Key Takeaways

Download this comprehensive guide to review:

  • The use of iPSCs to generate 3D models to investigate mechanisms of neurological disorders
  • The improvement of an in vitro cell model to study Alzheimer’s Disease
  • How a neuroblastoma cell model has been used to analyze cell death in response to drug sensitivity
  • How fibro-blasts taken from a healthy individual and an ALS patient were reprogrammed to iPSCs and differentiated

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