Monitoring the ex vivo activation of human T lymphocytes is key to developing an optimized and scalable adoptive cell therapy process.
This poster highlights the development of a large-scale, multiplexed assay using the Intellicyt® iQue Screener PLUS platform to assess T-cell activation over time by combining immunophenotyping, cell proliferation, and cytokine profiling in a single assay.
These large-scale experiments provide extensive T-cell activation profiles on multiple donors with rapid assay turnaround time. The use of these assays can provide valuable information for optimizing adoptive cell therapy development and manufacturing protocols.
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