Step 6: Bulk Drug Substance Filtration
Maximum Yield at Lowest Protein Adsorption
Sartopore® Platinum 0.2 μm is the ultimate PES filter for Bulk Drug Substance Filtration in modern single use processes as it offers the highest throughput due to its Twin™ Pleat structure, the highest protein yield due to permanently hydrophilic surface modification and requires 90% less flush volume prior to Integrity Testing.
PES Membrane with the Lowest Protein Adsorption
Sartopore® Platinum 0.2 μm third-generation PES membrane with its unique, permanently hydrophilic surface modification has one of the lowest protein adsorption profiles, increasing your target protein output for every batch.
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Sartopore® Platinum filter requires 90% less WFI flush volume with only 1 L needed for 5” (size 9) capsule for Integrity Testing, thanks to its unique, permanently hydrophilic surface modification. You can conveniently conduct post-sterilization; pre-use Integrity Testing with smaller flush bags, simplifying single-use assembly designs.
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Validate the viral reduction performance of Virosart® HF with our Confidence® Services: Highly purified viruses and expert knowledge.
Rapid and cost-effective single-use / hybrid solutions from early phase development through scale-up to commercial manufacturing.
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