Improved Efficiency with Label-Free Bio-Layer Interferometry (BLI) eBook | Sartorius

eBook: Improved Efficiency with Label-Free Bio-Layer Interferometry (BLI)

In collaboration with: American Pharmaceutical Review | Last updated: December 2023

Overview

Bio-Layer Interferometry (BLI) is a label-free technology for measuring biomolecular interactions. As an optical technique, it analyzes the interference pattern of white light reflected from two interfaces: a layer of immobilized protein on the biosensor tip and an internal reference layer. Even the slightest change in the number of molecules attached to the biosensor tip triggers an adjustment in the interference pattern, which can be measured in real time.

The articles in this eBook provide an overview of BLI technology and its pharmaceutical applications. Specifically, the articles explore the use of Octet® BLI systems and how they can be used to modernize quality control (QC) testing, increase efficiency, improve productivity, and meet validation requirements.

Download this eBook now to learn more about BLI technology.


  • Document type: eBook
  • Page count: 38
  • Read time: 60 minutes


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Contents of the eBook

  • Octet® Systems: Modernize Biopharmaceutical QC Testing to Increase Efficiency
  • Enhanced Productivity and Labor Efficiency in Lot Release and In-Process Testing of Biologics in GxP Laboratories
  • Octet® Systems in Ligand Binding Assays That Meet Compliance
  • Instrument Comparability Assessment: Kinetics Precision Assessment in Ligand Binding Assays on the GxP-Compliant Octet® RED96e and Octet® R8 Instruments
  • Octet® Potency Assay: Development, Qualification and Validation Strategies

This Resource is Designed for:

  • Analytical Lab Assistants
  • Engineers
  • Lab Researchers
  • Quality Control Scientists
  • Antibody Manufacturers

Applications Supported:

  • Label-Free Bio-Layer Interferometry (BLI)
  • Biopharmaceutical Quality Control (QC) Testing
  • Ligand Binding Assays
  • Octet® Potency Assays
  • Lot Release and In-Process Testing of Biologics

Complete the Form to Access the eBook