Virtual Demonstration and Conceptual Overview of the BioSMB Multi-Column Chromatography Platform
Biopharmaceutical manufacturers and CDMO/CMOs purifying mAbs are eager to simplify downstream operations. Traditional batch chromatography is more complex and requires more protein A resin. Multi-column chromatography (MCC) solutions offer a number of advantages.
The BioSMB platform based on multi-column chromatography principle provides an ideal opportunity to start exploring possible starting points in intensification. For customers seeking lower production costs with a single-use solution for clinical and commercial processing, BioSMB can reduce resin usage by up to 80% with minimal disruption to the accepted ways of doing chromatography today. This presents a considerable saving on operational expenditure, particularly when considering affinity capture steps.
In this virtual event, our Technology Expert Jason Forte, who has over five years of experience in helping customers set up the BioSMB platform in a field application specialist role and enabling them to design their intensified processes, will demonstrate the ease of installation of the single-use flow path and how it facilitates scale-up and walk through the automation software.
Key Learning Objectives
- A demonstration of the ease of installation, set-up, and main features of the BioSMB PD and Process systems
- How the software enables user-friendly processing
- Valve technology, flow path configuration, and consistent recipe handling between benchtop and GMP scale systems ensuring scalability
- How the BioSMB system offers a 3-5 fold increase in productivity
- How to yield up to 80% savings on chromatography resin costs with minimal disruption to the accepted ways of doing chromatography today
Meet Our Expert
Jason Forte
Product Specialist, Intensified Processing
Jason is a Product Specialist at Sartorius, focusing on intensified processing solutions. He has several years of experience with the BioSMB technology devoted to customer implementation of intensified and continuous technologies and the development of process control strategies. Prior to joining Sartorius in 2020, Jason served as a continuous processing engineer at Pall Biotech. Jason has an additional 3 years of experience in the industry focused on early-stage drug and process development. He holds a Doctor of Philosophy in Bioengineering from Worcester Polytechnic Institute, Worcester MA, USA.