Virus Counter® Platform | Sartorius

Virus Counter® Plus & Virotag® Reagents

The VirusCounter® Plus Platform is specialized in quantifiying viruses in a rapid, direct and precise manner

Our goal is to revolutionize virus quantification with the Virus Counter® Plus platform. By providing rapid, precise, and real-time measurement of virus concentrations, we aim to enhance research and development processes and to streamline manufacturing processes. With automated 96-well format processing, advanced fluorescence detection, and user-friendly software, the Virus Counter® Plus ensures efficient and reliable results, empowering scientists and manufacturers to achieve new levels of productivity and precision in their work.

The Virus Counter® Plus platform utilizes Virotag® reagents for precise virus detection and quantification. These reagents, are designed for specific and high-affinity labeling of viral proteins and nucleic acids. The straightforward staining process, combined with the platform’s advanced detection capabilities, ensures accurate measurement of virus particles in a variety of samples. This allows for reliable and consistent results, making Virotag® an essential component of the Virus Counter® Plus system.

  • Accelerate time-to-result and process development timelines with rapid titer insights
  • Highly reproducible results allow critical decision making with strong confidence
  • Advanced signal detection for higher sensitivity and improved precision

Virus Counter® Plus Platform

Discover the Virus Counter® Plus Platform: Your Efficient Solution for Rapid Virus Quantification

The Virus Counter® Plus platform revolutionizes virus quantification for industry, particularly in fields such as Advanced Therapeutics , Viral Vector manufacturing and Vaccines. Customers in cell and gene therapy rely on the Virus Counter® Plus for its rapid, accurate measurement of total virus particles, unlike traditional methods that are slow and imprecise. As viruses become crucial tools in gene therapy, vaccines, and cell modifications, the Virus Counter® Plus meets the growing and evolving market demands efficiently and effectively.

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Virotag® reagents are ready-to-use quantification kits

The Virotag® labeling system uses a rapid, no wash-assay workflow.

Virotag® reagent kits are optimized for use with the Virus Counter® Plus platform to detect and precisely enumerate viruses. Near real-time insights into virus titers allow optimization of development and manufacturing processes and improving virus yields.



Virotag® Reagents

Our Virotag® Reagents – The Ideal Quantification Solution

Virotag® reagents feature a straightforward, no-wash protocol for optimal virus staining. This enables rapid, direct, and precise virus quantification using the Virus Counter® Plus platform.

Virotag® AB Reagent

The Virotag® detection system provides mission-critical data in real-time. This novel technology enables direct, biologically specific quantification of viruses. by utilizing a fluorescently-labeled, high-affinity antibody that binds to a unique epitope expressed by your virus of interest.

Use the Virotag® reagents to label your virus samples and analyze on the Virus Counter® instrument.

  • High specificity due to antibody-based labeling system
  • Enables detection of viruses and virus like particles
  • Ready-to-use reagent with a simple no-wash protocol 

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Virotag® DY Reagent

The Virotag® DY detection system is a ready-to-use, simple, and universal approach for virus quantification. This reagent is compatible with all enveloped viruses, with single or double-stranded DNA or RNA genome. This universal reagent is based on a dual strain approach that identifies intact virus particles by simultaneous detection of protein and nucleic acid signals. The use of fluorogenic dyes eliminates the need to wash.

  • Universal detection method for enveloped viruses
  • Detect and identify virus particles with a dual signal approach
  • Ready-to-use reagent with a simple no-wash protocol

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Choose the Optimal Reagent for Every Virus Sample

Enveloped Virus

Virotag® DY ENV Reagent

Virotag® AB Reagent

Enveloped Virus (universal)

 

 

Baculovirus

 

  (Virotag BCVB)

Influenza A

 

  (Virotag INVA)

Influenza B

 

  (Virotag INVB)

Lentivirus

 

  (Virotag VSVG*)

Non-Enveloped Virus

Adeno-associated Virus 2

 

  (Virotag AAV2-3)

Adeno-associated Virus 3

 

  (Virotag AAV2-3)

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Non-Enveloped Virus

Virotag Reagent

Adeno-associated Virus 2

Virotag AAV2-3

Adeno-associated Virus 3

Virotag AAV2-3

* for VSV-G pseudotyped Lentivirus

If your sample is compatible with the universal Virotag® DY reagent and an antibody-based Virotag® reagent, please consult a specialist about your specific needs to choose the optimal reagents for your sample.


Download Brochure

Learn More About Virus Quantification

Highlight Assets

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Virus Counter Platform

Accelerate Vaccine Development With Rapid Total Particle Quantification

Watch Webinar Online
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The Impact of Rapid Virus Quantification - BPI Webcast

Learn more about the impact of rapid virus quantification in the development and manufacture of advanced therapies.

Watch Webcast
Application Note

Rapid, Real Time Quantification of Lentivirus Particles Using Antibody-Based Detection on the Virus Counter® 3100 Platform

PDF | 113.4 KB
Brochure

Meet the Virus Counter® Platform - Rapid, Direct, Biologically Relevant Virus Quantitation

PDF | 1.3 MB
Poster

Rapid Total Particle Quantification for Viral Families With High Potential for Pathogenic Emergence

PDF | 949.7 KB
Poster

Rapid, Real Time Quantification of Adeno-Associated Virus Particles Using Antibody-Based Detection on the Virus Counter® 3100

PDF | 1.4 MB

Q&A: Quantifying Viruses? Here’s What Matters Most

PDF | 174.8 KB

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