Cell Line Development Services | Sartorius

Speed Up Your Time-To-Clinic With Our Advanced 4Cell® CHO Platform Services

Get It Right The First Time

The 4Cell® CHO Platform comprises of individual services: Cell Line Development (CLD), Protein Characterization, and Cell Bank Manufacturing and Biosafety Testing. Plus, our new 4Cell® SmartCHO media is designed to support high performing clones generated by CLD.

Superior Performance: Up to 10g/L

Proprietary and superior CHO cell line development technology that ensures a robust and scalable bioprocess with high product yield (up to 10g/L for monoclonal antibodies) and quality.

Impressive Speed: RCB in 9 weeks

From DNA to Research Cell Bank (RCB) in only 9 weeks. No need for time-consuming media and process optimization or scalability studies. Regulatory ready documentation package.

Outstanding Reliability: 300+ projects

More than 300 cell line development projects. Benefit from our know-how and experience and get your cell line right the first time.

Low Financial Risk: Pay as you go

No hidden fees, no cancelation fees, no milestone payments.

State-of-the-art laboratories for rapid generation of stable cell lines

Join us for the virtual tour through our Cell Line Development Center of Excellence in Ulm, Germany and learn about the process of generating high-yielding stable cell lines in only 9 weeks.

Rapidly Generate High-Yielding, Stable Cell Lines

Sartorius offers a complete service with industry-leading technology aimed at the commercial manufacturing of protein therapeutics. Tour our state-of-the-art facility which features special laboratories designed to develop cell lines.

Article

Outsourcing CLD: Finding the Perfect Partner

Discover what multiple factors drug developers must be aware of before choosing a CLD partner.

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4Cell® CHO Platform Features

The 4Cell® CHO Platform Bundles Services and Media in a GMP Manufacturing-Ready Solution

The combination of Sartorius’ industry-leading technologies and services into one integrated solution accelerates your program and puts your molecule on the path to success.  

The unique 4Cell® CHO Platform consists of the following Sartorius solutions:

Cell Line Development Service using 4Cell® SmartCHO Media

Sartorius’ CHO Cell Line Development service targets commercial manufacturing of biopharmaceuticals. Our unparalleled cell line development technology combines 4 key components: Expression vector, host cell line, 4Cell® SmartCHO media, and upstream process design.

Protein Characterization Service

Sartorius’ protein characterization services are scaled to each phase of drug development. These services include development, qualification and validation of product characterization assays, such as cell-based potency assays, binding assays and physicochemical tests.

Cell Bank Manufacturing and Biosafety Testing

​The Sartorius cell banking platform was designed as a closed, sterile, single-use system with automated filling into vials to generate large banks. Plus, Sartorius has extensive experience in characterization of cell banks used in production of biologic drugs for protein-based therapies.

With the freedom to use the CMO of their choice for production, multiple satisfied clients have benefited from Sartorius CLD Service. The service offers exceptional flexibility at a reduced cost and enables clients to overcome typical obstacles that can delay manufacturing a first GMP batch.

Consult Our Experts

White Paper

From CLD to CDMO: A Case Study Demonstrating Successful Cell Line Tech...

Learn about the methodologies your processes need for successful Cell Line Technology Transfer.  

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Cell Line Development Webinar Series

Learn strategic approaches, best practices, critical considerations, and expert insights on-demand.

Browse CLD Webinars

Featured Resources

Cell Line Service
Webinar

How a Single Provider Can Reduce Protein Biologic Development Risk

In this webinar, Sartorius and Sonnet BioTherapeutics discuss the benefits of the Sartorius CHO Platform of integrated products and services.

Webinar

Next-Gen CHO Cell Line Development Services

Learn how an expert partner can help accelerate cell line development, reduce risk, and improve outcomes with advanced tools and technology.

Webinar

Power of the Right Cell Line Development Partnership

The right CLD partner can make or break a project — learn how SpikImm and Sartorius collaborated to accelerate development of a COVID-19 therapy.

Webinar

Webinar: Expand Your Capabilities with an Enhanced CLD Service Partner

This presentation will highlight key challenges and considerations during biopharmaceutical CLD and the impact early decision-making can have at later...

Webinar

The Cellca Story Evolution of a Cell Line Development Technology

This talk will tell the success story of Cellca and its cell line development technology from the beginnings over the acquisition by Sartorius in 2015...

Poster

Improved Clone Selection with our 4Cell® CHO CLD Platform

Early screening of high-producer clones optimizes cell growth and can achieve up to 10 g/L in 9 weeks.

Webinars

Early Identification of High Producers: Sartorius CLD Service Platform

CLD is critical in biopharma, but selecting high-performing clones is time-consuming. In this webinar from Sartorius, Dr. Yash Patel walks throug...

Brochure

4Cell® CHO Platform Service Package: The Fast Track to IND

PDF | 1.8 MB
Brochure

Cell Line Development Service

PDF | 740.0 KB
Datasheet

4Cell® CHO Media and Feed Portfolio

PDF | 1.4 MB
Brochure

cGMP Cell Bank Manufacturing and Characterization

PDF | 1.2 MB
Brochure

New Biological Entity - Product Characterization Services

PDF | 814.3 KB
Brochure

Comprehensive Media Solutions for Your Protein-Based Therapies

PDF | 1.0 MB
Poster

The 4Cell® CHO CLD Platform 

PDF | 2.5 MB

Consult Our Cell Line Development Experts