Mesenchymal Stem Cell Therapy Research & Development | Sartorius
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Innovative Tools for Streamlined MSC R&D Workflows

Maximize MSC Research with Deeper Insights, Automation, and Enhanced Characterization

Mesenchymal stem cells (MSCs) are adult stem cells isolated from various sources such as bone marrow, adipose tissue and umbilical cord. They are multipotent cells with the capacity to differentiate into cell types such as osteocytes (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and fat cells of adipose tissue (adipocytes).

MSCs secrete a host of chemical messengers, including chemokines, cytokines, growth factors, metabolic products and small molecules such as microRNAs (miRNAs), which act on neighboring cells to produce biological effects.

The potential of MSCs to differentiate into various cell types and their immunomodulatory functions make them attractive candidates for regenerative therapies and chronic inflammatory disease treatment.

Effective advanced cytotherapies require reliable equipment and bioprocesses to move from research to clinical phases and eventually gain regulatory approval. Challenges can include: 

  • Controlling variability to ensure reproducibility of experiments
  • Automating assays to understand and characterize MSCs and their therapeutic effects
  • Running assays at throughput to accelerate the development of insights
  • Characterizing the phenotype and function of MSCs and affected tissues to measure therapeutic effect of MSCs
  • Gaining insight into MSC therapeutic potential through extensive characterization to establish critical quality attributes (CQAs)
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Cell Culture Media

Buy 1, Get 1 Free Research Growth Factors & Cytokines

Use promo code SPRING24 for buy one, get one free on our entire line of RUO growth factors and cytokines before September 30.

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MSC Therapy Research & Development Benefits

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Comprehensive Characterization

Gain biological insights into MSC phenotypes and therapeutic effects through in-depth cell characterization

Control and Reproducibility

Ensure study reproducibility by effectively managing MSC donor, culture and reagent variability

Biosafety

Ensure patient safety with rapid detection of mycoplasma as well as bacteria and fungi in just three hours

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Featured MSC Therapy Research & Development Products

Cell selection and retrieval instrument with dual monitors

CellCelector Automated Cell Selection and Retrieval Platform

Fully automated solution for the identification, targeted isolation and passaging of the desired stem cell colonies or clones.

Automated counting and picking of individual stem cell colonies to access myeloid vs. erythroid colonies, differentiation state, gene expression profiles or gene mutations.

Explore Clonal Stem Cell Picking

Incucyte® Live Cell Analysis uses whole-well, label-free imaging to scan clones and verify monoclonality.

Incucyte® Live-Cell Analysis Platform

Enables real-time, live-cell analysis directly inside your incubator and deeper, physiologically relevant information about your cells. Never miss powerful insights again with the Incucyte® Live-Cell Analysis System, software, reagents and consumables.

  • Study complex immune cell interactions, synaptic activity in neuronal co-cultures, apoptosis, proliferation and much more -with a single platform.
  • Enjoy walk-away convenience as images are automatically acquired and analyzed in microplate format, up to six in parallel.
  • Exosomes and extracellular vesicles (EVs) uptake assays

Explore Live Cell Assays

iQue Advanced Flow Cytometry Platform

iQue® 3 High-Throughput Cytometry Platform

The iQue® 3 HTS Platform is an integrated instrument, software and reagent system that enables rapid, high-content, multiplexed analysis of cells and beads in suspension.

  • MSC phenotypic and functional analysis

  • Immunomodulation and cytokine profiling assessment

Explore High-Throughput Cytometry

 Top down view of Sartorius Microsart ATMP Mycoplasma qPCR Mycoplasma Detection Kit. box and contents

Microsart® ATMP Mycoplasma — Rapid Real-time PCR Mycoplasma Detection Kit

Microsart® Mycoplasma qPCR detection kits: a rapid and guideline-compliant solution for mycoplasma detection. These kits are fast, highly specific, sensitive, and compliant with international guidelines.

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An open box of Sartorius Microsart ATMP Sterile Release and its contents

Microsart® ATMP Sterile Release Detection Kit

Rapid Bacteria and Fungi Detection in Only 3 Hours with Microsart® ATMP Sterile Release Kit. The qPCR-based kit detects a broad range of gram-positive and gram-negative bacterial and fungal contaminants.

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Mesenchymal Stem Cell Media

MSC NutriStem® XF supports the isolation and expansion of hMSCs, providing high-quality cultures for research and cell-based therapies.
•    Xeno-free, serum-free  
•    Superior proliferation rate  
•    Maintain cell characteristics and differentiation potential
•    Custom scale-up and optimization services
•    Smooth transition from RnD to manufacturing
•    Scientific and regulatory support
•    cGMP manufactured
•    DMF available


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Featured Resources

MSC Therapy Research & Development Resources

Incucyte® 21 CFR Part 11 Software Module

Secure and configurable software module to track all system events and user actions.

Fully automated image-based single cell and colony picking for stem cells
Application Guide

Fully Automated Image-Based Single Cell and Colony Picking

Stem cells play an important role in the field of regenerative medicine for a wide range of biomedical and pharmaceutical research applications

First Final Release Test of ATMPs Prior to Treatment Validation of a qPCR-Based Rapid Sterility Test
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Rapid Sterility Testing for Cell Therapy Quality Control Poster

In this poster, a validation study was designed to evaluate bacterial and fungal detection capability.

MSC Functional and Phenotypic Characterization Solutions
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MSC Functional and Phenotypic Characterization Solutions

See this collection of cell analysis solutions and cell culture media as well as rapid testing for biosafety.

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