Gain expert insight on cell therapy strategic approaches, best practices and critical considerations to advance your next breakthrough treatment from discovery to the clinic in this curated, on-demand collection.
View this inforgraphic to learn how CAR-T therapy works, the R&D workflow, and more.
Understand methods for the characterization, maintenance, scale up, and selection of ideal iPSCs in a combined workflow approach
Stem cells play an important role in the field of regenerative medicine for a wide range of biomedical and pharmaceutical research applications
Octet® BLI to measure and characterize CRISPR/Cas mediated binding and Gene activation
This study investigates the expansion of T cells by comparing the growth and anti-cancer effects of serum-free and serum-containing media.
Learn how to maintain iPSC-derived neuronal & microglial models and a method for non-invasive, continuous monitoring of culture health.
Discover a simplified and robust method for differentiating iPSCs into hepatic organoids using Sartorius RUO Growth Factors and Cytokines.
Gain in-depth insights into the impact of growth factors and cytokines on organoid development, alongside real-time data analysis using the Incucyte®...
Effectively use growth factors & cytokines with iPSC media to preserve pluripotency, support growth & increase time between feedings.
This application note discusses and characterizes of the interaction between the SARS-CoV-2 Nucleocapsid (N) protein and human chemokines.
Translational In Vitro Models for Studying Human Development & Disease
Learn about an accelerated and streamlined workflow approach for the culture, monitoring and characterization of iPSCs.
Combined iQue® 3 and Incucyte® live-cell analysis workflow approach for evaluating iPSC pluripotency and differentiation.
This application note presents a benchmark study comparing the capabilities of two different qPCR kits for the detection of Mycoplasma.
To Gain Additional Insights into the Mechanisms of Immune Cell Killing of Tumor Cells
Quantitative live-cell analysis for optimization of culture conditions and evaluation of cell health in human iPSC-derived neurons.
Using Live Cell Analysis
Pipetting practices can greatly affect the reproducibility of sample prep or the outcome of cell assays. Learn best practices here.
Sartolab®️ RF50, Sartoclear Dynamics®️ Lab V50, and other manufacturers’ filters were evaluated for clarification of lentiviral vectors.
Learn a real-time, image-based method to quantify the infectious titer of anti-CD19 CAR lentiviral vectors using the Incucyte® Live-Cell Analysis Syst...
Two High-Throughput Screening by Cytometry solutions to address problems with traditional methods for measuring T cell response in 3D models
Learn how Sartoclear Dynamics® Lab filtration is a viable approach to clarifying AAV crude cell lysates.
The recent FDA approval of the very first CAR-T therapy marks a significant milestone in the field of cell and gene therapy
Cell and gene therapy is one of the most promising areas of biomedical research. In this post, we will focus on the role of advanced flow cytometry in CAR-T cell development.
Learn about the importance of CQAs, the challenge of selecting the right ones and how the right equipment can simplify the process.
Biologists spend huge amounts of time studying cells under the microscope. But how can we derive quantitative insights from complex cell morphology data?
Cancers have a way of outmaneuvering I-O therapies. To win, scientists are using data-rich tools to understand the complex relationship between cancer and immune cells.
When it comes to laborious manual protocols, single-cell isolation is a top contender. Learn how one automated single-cell selection and retrieval platform is changing the game.
While fluorescence-activated cell sorting (FACS) and limiting dilution have traditionally been used for single cell cloning, many are turning to automated, image-based solutions.
Mesenchymal stem cells secrete tiny extracellular vesicles with big potential for therapeutic applications but choosing the right media to support their production is essential.
Discover innovative solutions for both upstream and downstream workflows for lentivirus production.
Simplify lab-scale cell therapy R&D workflows with our full ensemble of state-of-the-art solutions
Discover more about our range of high-quality, animal-derived component-free RUO Growth Factors & Cytokines
This eBook features chapters on upstream production, downstream processes, quality control assays and analytics for lentiviral vectors.
Gaining Critical Characterization Insights for Development of CAR-T Therapies for Solid Tumors
Discover how cytometry enables you to expedite CAR-T discovery.
This eBook focuses on the use of advanced flow cytometry and live-cell analysis in CAR-T development
This Sartorius eBook is an informative guide for choosing the right water purification system for your laboratory.
Learn key tips for effectively and efficiently developing novel cell therapies with a maximized chance of clinical success.
Learn five tips for preventing mycoplasma contamination in the cell cultures in this easy-to-understand infographic.
Ensure the highest patient safety with real-time PCR-based rapid sterility testing. Learn more in this infographic.
Here we describe image-based, immune cell-killing assays of 3D tumour spheroids, geared for assessing the efficacy of novel immune-modulators.
Download the scientific poster to learn more about how to reduce the variance with best sample preparation practices to provide more reliable and repr...
This study highlights the power of the iQue® Screener PLUS platform to rapidly characterize multiple endpoints and the ForeCyt® Software to...
Using High Throughput Flow Cytometry and an Optimized Multiplexed Assay
In this poster, a validation study was designed to evaluate bacterial and fungal detection capability.
Learn how to monitor, maintain and culture stem cells consistently and reliably while retaining high levels of cell health in this webinar.
This webinar explores Sartorius solutions for cell therapy workflows, focusing on 21 CFR Part 11 software for compliance simplification.
Watch this on-demand webinar to explore how body feed filtration can improve your clarification processes.
Human induced pluripotent stem cells (hiPSCs) are an invaluable resource in the field of regenerative medicine, with hiPSC reprogramming providing a p...
In this webinar, Prasad Adusumilli, Stephen Gottschalk, and Leonid Metelitsa discuss the challenges of targeting CAR T and related ACT platforms to th...
An overview of gene-modulation technologies and functional genomic screens
For a closer look at the design, development, and success of CAR T-cell therapy and bispecific antibodies, a panel of experts come together to discuss...
Understand the importance of advanced cell models for development of novel treatments and personalized medicine in this expert panel webinar.
This webinar provides an overview of advanced cell analysis techniques and details how to combine them, for maximum insight into T cell biology.
See the Octet® AAVX Biosensor in comparison to an in-house assay on the Octet BLI platform.
Learn about challenges with liquid handling in cell and gene therapy processes and novel solutions that simplify aliquoting.
Driving Biological Insight and Productivity With Real-Time Non-Invasive Phenotypic Assays
Learn about streamlined in vitro assays used for phenotyping and functional assessment of modified CAR-T cells, with three case studies.
Antibody and other protein therapeutics are a major focus in drug discovery pipelines today.
Neurobiology applications using live-cell analysis for studies in both human induced pluripotent stem cells (iPSCs) and primary cell models.
Cell-based therapies provide new opportunities to treat disease and offer hope to patients in need.
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