Webinar: Accelerate Process Optimization by Combining Cell Culture with Titer Measurements
Cell line development involves screening thousands of clones to find those that are stable, produce high yields of the bioproduct and exhibit desired critical quality attributes (CQAs). While there are multiple CQAs that need to be monitored early in the development process, product yield, cell count and viability assessment remain the main attributes by which process conditions are optimized. Analytical techniques that can be incorporated into cell line selection workflows can greatly accelerate studies. In this webinar, experts from Sartorius demonstrate the power of using the Ambr® 15 Cell Culture system together with an Octet® instrument to identify favorable yield conditions.
Learning Objectives:
- Analytical tools and techniques to accelerate cell line development and selection workflows
- Benefits of using the Ambr® 15 system with the Octet® instrument to optimize CQAs
Dirk Müller, Ph.D.
Manager of Media & Process Development
Sartorius
Dirk Müller heads a product development team at the Cell Line, Media & Testing Solutions (CMTS) unit of Sartorius. His team develops media and different process formats for CHO cells. Before joining Sartorius, Dirk worked in several positions at Insilico Biotechnology, a company specializing in optimization of bioprocesses using predictive cell models. Dirk holds a master’s in chemical and process engineering and a Ph.D. in biochemical engineering.
Lukas Klein
Scientist
Sartorius
Lukas Klein is a scientist in the Bioprocess Development group at Sartorius and holds a master’s degree in biomedical sciences. His professional experience includes process development and optimization, fed-batch and perfusion processes, and cell line development.