Poster: Accelerating Cell Line Development with an Efficient, Combined Platform Approach
Cell line development (CLD) involves the screening of thousands of clones to find those that are stable, produce high yields of bioproduct and have desired critical quality attributes (CQAs). Screening and process optimization activities are typically carried out on a small scale in bioreactor cultures to ensure results translate to downstream processes. Performance data is primarily based on cell growth, cell viability, metabolite analysis and product titer. Data is assessed over the entire culture process duration.
This poster illustrates the power of using the Ambr® 15 Cell Culture system (with an integrated Vi-CELL XR) and Ambr® Analysis Module - together with the Octet® BLI platform - to identify optimum yield conditions in media screening and process optimization experiments.
Learn more about Sartorius solutions for Cell Line Development at https://www.sartorius.com/cld.
